WHAT ARE THE DAMAGES CAUSED BY FABRY DISEASE

The classical form of Fabry disease is characterised by chronic and/or acute painful symptoms already in infancy as well as remarkable fatigue. This deeply influences everyday life and limits everyday activities.

In addition, altered sweating may worsen those problems determining frequent increases in temperature, overheating after exercise and inability to withstand temperature changes.

Other symptoms affecting the gastrointestinal system, are abdominal cramps, diarrhoea, nausea.

The main problems however derive from the accumulation of GL-3 in the kidney, heart and brain which can lower remarkably the patient's quality and expectation of life. The decrease in quality of life is due not only to the clinical involvement of the disease, but also to the state of depression, low self-esteem and desperation often arising in these situations.